FIELD: biotechnology.
SUBSTANCE: method of reprogramming somatic mammalian cells is proposed, comprising bringing the mammalian somatic cell into contact with reprogramming factors selected from the group consisting of: (i) Oct4; (ii) Oct4 and Klf4; (iii) Oct4, Klf4 and Sox2, and with Wnt-conditioned medium or activator of the pathway Wnt.
EFFECT: invention can be used for obtaining induced pluripotent stem cells in order to treat or prevent a medical pathological state in an individual.
10 cl, 1 tbl, 5 dwg, 8 ex
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