FIELD: chemistry.
SUBSTANCE: invention describes pyrrolo[2,3-d]pyrimidine derivatives of formula 
(I) or a pharmaceutically acceptable salt thereof, where R1 is C1-4 alkyl, optionally substituted with a hydroxy group, as well as a crystalline form A of a salt of N-methyl-1-{trans-4-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexyl} methane sulphonamide with maleic acid. Disclosed also is a method of producing a salt of N-methyl-1-{trans-4-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexyl} methane sulphonamide with maleic acid.
EFFECT: improved properties of the composition, having inhibiting activity on Janus kinase and a method of treating allergic reactions, allergic dermatitis, atopic dermatitis, eczema or itching in mammals.
17 cl, 7 ex, 4 tbl, 3 dwg
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