SPIRO-FUSED PIPERIDINE DERIVATIVES FOR APPLICATION AS INHIBITORS OF EXTERNAL MEDULLAR LAYER POTASSIUM CHANNEL Russian patent published in 2018 - IPC C07D471/10 A61K31/438 A61P13/12 A61P9/00 

Abstract RU 2642066 C2

FIELD: pharmacology.

SUBSTANCE: invention relates to compounds of formula I .

EFFECT: new compounds of formula I are obtained which are inhibitors of the ROMK channel and which can be used in hypertension treatment.

11 cl, 5 tbl, 85 ex

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RU 2 642 066 C2

Authors

Din Fa-Syan

Dun Shuchzhi

Fri Dzhessika

Gu Sin

Tszyan Tszinlun

Pasternak Aleksander

Tan Khajfyn

U. Chzhitsaj

Yuj Yan

Sudzuki Takao

Dates

2018-01-24Published

2013-07-25Filed