FIELD: biotechnologies.
SUBSTANCE: single-domain antibody (nanoantibody) is proposed, which specificaly binds a mucin 1 protein (MUC1) of a human being and characterised by a full amino acid sequence. Also the method is considered to detect a MUC1 protein in biological fluids of a human being with usage of a nanoantibody according to the invention.
EFFECT: invention may find further application in diagnostics and therapy of cancer.
3 cl, 3 dwg, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| NANOANTIBODY SPECIFICALLY BINDING CEA PROTEIN, METHOD OF ITS USAGE FOR DETECTION OF THIS PROTEIN | 2012 |
|
RU2493166C1 |
| SINGLE-DOMAIN MINI-ANTIBODY aHER2/aSKBR3-1, SPECIFICALLY BINDING EPIDERMAL GROWTH FACTOR RECEPTOR HER2/ERBB2/neu AND CAPABLE TO PENETRATE THROUGH THIS INTERACTION INTO TARGET CELLS (INTERNALISED), METHOD OF PRODUCTION OF THIS ANTIBODY AND METHOD OF DETECTION OF PROTEIN HER2/ERBB2/neu AND CELLS EXPRESSING THIS PROTEIN IN INCREASED AMOUNT, USING MINI-ANTIBODY aHER2/aSKBR3-1 | 2012 |
|
RU2522929C2 |
| SINGLE-DOMAIN ANTIBODY aMts1 SPECIFICALLY BINDING PROTEIN S100A4/Mts1, METHOD FOR PREPARING AND USING FOR DETECTION OF THIS PROTEIN | 2012 |
|
RU2484096C1 |
| NANOANTIBODIES BINDING CHLAMYDIA TRACHOMATIS ANTIGEN, METHOD OF INHIBITING INFECTION CAUSED BY CHLAMYDIA TRACHOMATIS | 2012 |
|
RU2487724C1 |
| NANOANTIBODIES aMh1, aMh2 BINDING ANTIGEN OF MYCOPLASMA HOMINTS, METHOD OF PRODUCING THEM, METHOD OF TREATING MYCOPLASMA HOMINIS INFECTION | 2011 |
|
RU2484095C1 |
| RECOMBINANT SINGLE-DOMAIN ANTIBODIES SPECIFICALLY BINDING F4/80 PROTEIN, METHOD FOR PRODUCTION THEREOF AND USE FOR DETECTION OF SAID PROTEIN | 2015 |
|
RU2599423C1 |
| VEGF BINDING V93 NANOANTIBODY AND METHOD OF OBTAINING SAID ANTIBODY, V93-CODING NUCLEOTIDE SEQUENCE AND VECTOR CONTAINING SAID SEQUENCE, ENDOTHELIAL CELL PROLIFERATION INHIBITION METHOD | 2008 |
|
RU2395522C1 |
| VEGF BINDING V9 NANOANTIBODY AND METHOD OF OBTAINING SAID ANTIBODY, V9-CODING NUCLEOTIDE SEQUENCE AND VECTOR CONTAINING SAID SEQUENCE, ENDOTHELIAL CELL PROLIFERATION INHIBITION METHOD | 2008 |
|
RU2395521C1 |
| RECOMBINANT SINGLE-DOMAIN ANTIBODIES SPECIFICALLY BINDING HUMAN INTERLEUKIN-6, METHOD FOR THEIR PREPARING AND USING FOR DETECTION OF THIS PROTEIN | 2015 |
|
RU2603269C1 |
| TRIMERISED SINGLE-DOMAIN ANTIBODY THAT SPECIFICALLY BINDS WITH GLYCOPROTEIN G OF RABIES VIRUS, NEUTRALISING RABIES VIRUS | 2013 |
|
RU2533802C1 |
