FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to cosmetology and dermatology, and represents a water-based formulation for local application for treating acne, containing water, a water-miscible organic solvent and benzoyl peroxide, wherein the organic solvent concentration is 1-4 times higher than the benzoyl peroxide concentration in the formulation; the water and organic solvent concentrations are related as at least 7:1, preferentially at least 10:1, more preferentially at least 20:1; the benzoyl peroxide concentration in the formulation makes less than 5.0 wt %, but at least 1.0 wt %.
EFFECT: invention provides the clinical effectiveness with the reduced active agent concentration, as well as reduced irritant action.
27 cl, 4 ex, 3 tbl
Authors
Dates
2013-09-27—Published
2009-06-03—Filed