FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to chemical-pharmaceutical industry. The method consists in the fact that ADS-2 is mixed with alcohol; the prepared azeotrope mixture is stripped in vacuum. The ADS-2 is mixed with alcohol in relation 1:2-1: 2,25. The above alcohol is either isopropyl or ethyl, or butyl alcohol. The prepared azeotrope mixture is stripped at temperature 40°C and residual pressure 10-20 mm Hg for 20-40 minutes.
EFFECT: invention provides a stabilised form of the ADS-2 which contains no more than 66% of water that enables considerably decreasing the therapeutic doses and provides the sedimentation for two-year storage.
4 cl, 3 tbl, 3 dwg, 3 ex
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Authors
Dates
2013-10-10—Published
2012-06-20—Filed