METHOD FOR PREPARING STABILISED FORM OF FRACTION 2 ANTISEPTIC DOROGOV'S STIMULATOR (ADS-2) Russian patent published in 2013 - IPC A61K35/12 

Abstract RU 2494750 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to chemical-pharmaceutical industry. The method consists in the fact that ADS-2 is mixed with alcohol; the prepared azeotrope mixture is stripped in vacuum. The ADS-2 is mixed with alcohol in relation 1:2-1: 2,25. The above alcohol is either isopropyl or ethyl, or butyl alcohol. The prepared azeotrope mixture is stripped at temperature 40°C and residual pressure 10-20 mm Hg for 20-40 minutes.

EFFECT: invention provides a stabilised form of the ADS-2 which contains no more than 66% of water that enables considerably decreasing the therapeutic doses and provides the sedimentation for two-year storage.

4 cl, 3 tbl, 3 dwg, 3 ex

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RU 2 494 750 C1

Authors

Engashev Sergej Vladimirovich

Sidorin Dmitrij Nikolaevich

Rogova Natal'Ja Viktorovna

Remizova Natal'Ja Jur'Evna

Engasheva Irina Viktorovna

Dates

2013-10-10Published

2012-06-20Filed