FIELD: medicine.
SUBSTANCE: invention refers to a contrast agent for magnetic resonant and X-ray diagnostic agent for magnetic resonant tomography (MRT) and X-ray computed tomography (XRCT). The above agent contains complex ferric oxide in the concentration of 600 mg/ml, citric acid 2.4 mg/l for stabilising the particle size of complex ferric oxide within the range of 5-10 nm, sodium citrate 140 mg/ml for stabilising the contrast agent structure, polyethylene glycol in the concentration of 160 g/l and water for injections 460 mg/ml. The invention also refers to a method for preparing the above contrast agent wherein ferric salts are mixed with ammonium hydrate and citric acid added. That is followed by introducing polyethylene glycol with added water-dissolved sodium citrate while stirring thoroughly; non-dissolved sodium citrate is cooled and filtered.
EFFECT: group of the declared inventions provides more effective diagnostic study ensured by visualising with respect to relaxation time, as well as provides the lower concentration of the administered contrast agent.
3 cl, 1 dwg, 3 ex
Title | Year | Author | Number |
---|---|---|---|
MAGNETIC RESONANT AND RADIOPAQUE CONTRAST AGENT BASED ON COMPLEX FERRIC OXIDE AND METHOD FOR PRODUCING THEREOF | 2009 |
|
RU2419454C1 |
CONTRAST AGENT FOR T AND/OR T MAGNETIC RESONANT SCANNING AND METHOD FOR PREPARING IT | 2011 |
|
RU2471502C1 |
METHOD FOR PREPARING A PREPARATION FOR DIAGNOSING NEW GROWTHS BY MAGNETIC RESONANCE IMAGING | 2019 |
|
RU2723894C1 |
PREPARATION FOR DIAGNOSING NEW GROWTHS BY MAGNETIC RESONANCE IMAGING | 2019 |
|
RU2723932C1 |
T1 CONTRAST AGENT BASED ON ULTRATHIN IRON OXIDE NANOPARTICLES FOR MAGNETIC RESONANCE IMAGING | 2019 |
|
RU2794613C1 |
DIAGNOSTIC TECHNIQUE FOR GLIOBLASTOMA MULTIFORME BY MAGNETIC RESONANCE TOMOGRAPHY | 2012 |
|
RU2530762C2 |
METHOD OF PRODUCING NANODISPERSED MAGNETOACTIVE RADIO-OPAQUE AGENT | 2018 |
|
RU2687748C1 |
METHOD FOR PREPARING A PREPARATION BASED ON MAGNETIC NANOPARTICLES (MNCH) OF IRON OXIDE FOR MRT-DIAGNOSIS OF NEOPLASMS | 2017 |
|
RU2659949C1 |
CONTRAST AGENT FOR MAGNETIC RESONANCE TOMOGRAPHY | 2011 |
|
RU2465010C1 |
NANOPARTICLE CONTAINING ITS MAGNETIC RESONANCE IMAGING CONTRAST AGENT AND LIGAND COMPOUND | 2018 |
|
RU2767430C2 |
Authors
Dates
2013-11-10—Published
2012-04-23—Filed