MAGNETIC RESONANT AND X-RAY CONTRAST AGENT, AND METHOD FOR PREPARING IT Russian patent published in 2013 - IPC A61K49/04 A61K49/18 B82B1/00 B82B3/00 

Abstract RU 2497546 C1

FIELD: medicine.

SUBSTANCE: invention refers to a contrast agent for magnetic resonant and X-ray diagnostic agent for magnetic resonant tomography (MRT) and X-ray computed tomography (XRCT). The above agent contains complex ferric oxide in the concentration of 600 mg/ml, citric acid 2.4 mg/l for stabilising the particle size of complex ferric oxide within the range of 5-10 nm, sodium citrate 140 mg/ml for stabilising the contrast agent structure, polyethylene glycol in the concentration of 160 g/l and water for injections 460 mg/ml. The invention also refers to a method for preparing the above contrast agent wherein ferric salts are mixed with ammonium hydrate and citric acid added. That is followed by introducing polyethylene glycol with added water-dissolved sodium citrate while stirring thoroughly; non-dissolved sodium citrate is cooled and filtered.

EFFECT: group of the declared inventions provides more effective diagnostic study ensured by visualising with respect to relaxation time, as well as provides the lower concentration of the administered contrast agent.

3 cl, 1 dwg, 3 ex

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RU 2 497 546 C1

Authors

Akopdzhanov Artur Gennad'Evich

Naumenko Vladimir Jur'Evich

Panov Vadim Olegovich

Shimanovskij Nikolaj L'Vovich

Dates

2013-11-10Published

2012-04-23Filed