FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to a crystalline anhydrous form II of a 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolinon-2(1H)-one lactic acid salt, as well as to a method for preparing it, and a pharmaceutical composition inhibiting receptor VEGFR2 and FGER3 activity, on the basis of the above compound.
EFFECT: what is prepared is the new form of the 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolinon-2(1H)-one lactic acid salt and the pharmaceutical composition thereof, which can find application in medicine, such as cancer.
9 cl, 6 dwg, 3 tbl, 4 ex
| Title |
Year |
Author |
Number |
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