METHOD FOR SIMULATING CHRONIC INFECTED BONE WOUND Russian patent published in 2013 - IPC G09B23/28 

FIELD: medicine.

SUBSTANCE: bone defect is formed along the bone; the museum strain Staphylococcus Aureus No.5 culture in the amount of 40-45 mln CFU per 1 kg of experimental animal's body weight mixed with 0.1 ml of sterile silica sand are placed therein. Three days later, necrotic mass and purulent matter are removed from the bone defect. The wound is re-infected with the same culture in a dose of 20-25 mln CFU per 1 kg of body weight. The wound is further preserved in the form of a fistula.

EFFECT: method minimises a risk of fracture of the operated bone, animal death caused by septic shock and reduces length of the experiment.

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