DIFFERENTIAL DIAGNOSTIC TECHNIQUE FOR PURULENT AND SEROUS MENINGITES IN CHILDREN Russian patent published in 2013 - IPC G01N33/50 G01N33/48 

FIELD: medicine.

SUBSTANCE: method consists in evaluating the microbicidal activity of neutrophilic leucocytes, myeloperoxidase, cytochrome oxydase, acid phosphatase in the spinal fluid of the patients with purulent and serous meningites using spectrophotometric analysis. If the myeloperoxidase values fall within the range of 0.18-0.2 standard units, purulent meningitis is diagnosed, while serous meningitis is shown by the values of 0.059-0.061 standard units. The cytochrome oxydase activity being 0.49-0.57 standard units testifies to purulent meningitis, while the values of 0.186-0.174 standard units show serous meningitis. The spinal fluid acid phosphatase activity falling within the range of 0.14-0.18 standard units, purulent meningitis shall be considered, while the range of 0.069-0.071 standard units makes serous meningitis be diagnosed.

EFFECT: using the declared method enables more accurate diagnosis of purulent and serous meningites in children.

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