FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions discloses chimeric polypeptides, based immunogenic compositions, as well as methods for increasing milk and lean meat production involving vaccination with the above peptides. The chimeric polypeptides possess the immunogenicity of somatostatin and comprise an amino acid sequence of somatostatin-14 related to an inactive and shortened polypeptide of chloramphenicol acetyl transferase wherein somatostatin-14 is bound to inactive chloramphenicol acetyl transferase by means of a spacer.
EFFECT: given peptides possess better immunogenicity that enables using them in smaller doses in treating cows and farm animals.
11 cl, 4 dwg, 6 ex
| Title | Year | Author | Number |
|---|---|---|---|
| COMPOSITIONS AND METHODS FOR IMPROVING SOMATOSTATIN IMMUNOGENICITY IN TREATING GROWTH HORMONE AND INSULIN-LIKE GROWTH FACTOR DEFICIENCY | 2009 |
|
RU2519051C2 |
| RECOMBINANT PROTEIN GBD-SSTAD-SSTAD, A METHOD FOR PRODUCTION AND USE THEREOF | 2019 |
|
RU2722849C1 |
| FMDV VACCINES BASED ON A RECOMBINANT ADENOVIRAL VECTOR AND USE THEREOF | 2017 |
|
RU2725495C2 |
| VACCINE AGAINST HERPES SIMPLEX VIRUS TYPE 2: COMPOSITIONS AND METHODS FOR TRIGGERING IMMUNE RESPONSE | 2010 |
|
RU2585961C9 |
| RECOMBINANT SOMATOSTATIN-CONTAINING PROTEIN, METHOD FOR PRODUCTION, INJECTING DRUG TO INCREASE MEAT AND DAIRY EFFICIENCY OF AGRICULTURAL ANIMALS, AND METHOD FOR DRUG APPLICATION | 2016 |
|
RU2614115C1 |
| ACTIVE ANGIOGENESIS-PREVENTING IMMUNETHERAPY | 2003 |
|
RU2329824C2 |
| FMDV-E2 FUSION PROTEINS AND USE THEREOF | 2016 |
|
RU2714428C2 |
| IMMUNOGENIC COMPOSITIONS FOR IMMUNIZATION OF PIGS AGAINST CIRCOVIRUS TYPE 3 AND METHODS OF PRDUCTION AND APPLICATION THEREOF | 2016 |
|
RU2744193C2 |
| CH3 IGE PEPTIDE VACCINE | 2009 |
|
RU2495049C2 |
| COMPOSITIONS OF RECOMBINANT CDV AND ITS USE | 2011 |
|
RU2567337C2 |
