METHOD OF TREATING SPASTICITY ACCOMPANIED BY IMPROVED CONSCIOUSNESS IN PATIENTS IN VEGETATIVE STATE Russian patent published in 2013 - IPC A61K8/64 A61K35/66 A61P21/00 A61P25/28 A61P43/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to neurology, and may be used for treating spasticity accompanied by improved consciousness in the patients in the vegetative state. That is ensured by administering Xeomin (botulinumtoxinA free from complexing proteins) into the spastic muscles of all the extremities and related body segments regardless of the contractions in total dose of 400-1300 units. The dose shall not exceed 24 unit/kg of body weight in 1-3 stages. The stages follow at least every 3 days. Every 1-day stage involves administering 5-50 units in each accessible muscle or muscle group with the maximum tone in max. total dose 500 units dissolved in 12.5 unit/ml. The injections are distributed uniformly along the area without electromyography. The following courses are similar if observing spasticity and/or if clinically reasonable. The length of one course is up to 3 weeks.

EFFECT: method enables improving the therapeutic effect in the vegetative states.

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