COMPOUNDS DERIVED FROM TAURINE, METHODS FOR PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS Russian patent published in 2013 - IPC C07C309/14 C07D209/18 A61K31/10 A61K31/404 A61P29/00 

Abstract RU 2502729 C2

FIELD: chemistry.

SUBSTANCE: invention relates to novel compounds derived from taurine having formula , wherein R is selected from 2-(6-methoxy-2-naphthyl)propionic acid, [1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid and salts thereof. The invention also relates to a method of producing compounds of formula (I) by reacting taurine with a compound belonging to a group of non-steroid anti-inflammatory preparations comprising 2-(6-methoxy-2-naphthyl)propionic acid, [1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid, in the presence of a catalyst in a corresponding organic medium, and anti-inflammatory pharmaceutical compositions containing at least one compound of formula I, having non-steroid anti-inflammatory activity.

EFFECT: improved characteristics of compounds.

8 cl, 4 tbl, 10 dwg, 6 ex

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RU 2 502 729 C2

Authors

Visioli Ehdnir De Olivejra

Chin' Chun Man'

Menegon Renato Farina

Blau Lorena

Santos Khean Leandro Dos

Longo Marija Do Karmo

Dates

2013-12-27Published

2009-04-09Filed