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2 502 805

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IPC

C12P21/02(2006-01-01)

C12N15/09(2006-01-01)

C12N15/81(2006-01-01)

C12N1/19(2006-01-01)

C07K14/39(2006-01-01)

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Application

2012139788/10, 2012-09-18

(24)

Start date

2012-09-18

(22)

Actual filing date

2012-09-18

(45)

Published

2013-12-27

(72)

Inventor

Kozlov Dmitrij GeorgievichMolchanova Dar'Ja ViktorovnaGubajdullin Irek Il'JasovichCheperegin Sergej EhduardovichEfremov Boris DmitrievichTjurin Oleg Vladimirovich

(73)

Holder

Federal'Noe Gosudarstvennoe Unitarnoe Predprijatie Nauchno-Issledovatel'Skij Institut Genetiki I Selektsii Promyshlennykh Mikroorganizmov"

MICROBIOLOGICAL SYNTHESIS METHOD OF TARGET RELEASED PROTEIN IN YEAST Saccharomyces cerevisiae Russian patent published in 2013 - IPC C12P21/02 C12N15/09 C12N15/81 C12N1/19 C07K14/39

Abstract RU 2502805 C1

FIELD: biotechnologies.

SUBSTANCE: method involves cultivation in the appropriate conditions of yeast Saccharomyces cerevisiae and release of target protein; besides, release is directed with leader polypeptide, which has amino acid sequence SEQ ID NO1 and representing a variant of a pro-area of leader polypeptide of protein PpPIRl Pichia pastoris.

EFFECT: invention enlarges the range of methods for obtaining target protein in yeast Saccharomyces cerevisiae and increases possibilities for effective synthesis of such proteins.

2 dwg, 4 ex

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RU 2 502 805 C1

Authors

Kozlov Dmitrij Georgievich

Molchanova Dar'Ja Viktorovna

Gubajdullin Irek Il'Jasovich

Cheperegin Sergej Ehduardovich

Efremov Boris Dmitrievich

Tjurin Oleg Vladimirovich

Dates

2013-12-27—Published

2012-09-18—Filed