FIELD: chemistry.
SUBSTANCE: invention relates to novel 5-fluorouracil derivatives of general formula (I) or pharmaceutically acceptable salts thereof. In general formula 
(I), R1 denotes a hydrogen atom or a protective hydroxy group which is selected from a C1-C6aliphatic acyl group; C5-C6 alicyclic acyl group; aromatic acyl group which is selected from a benzoyl group or a halogen-benzoyl group, R2 denotes a lower alkoxy-lower alkyl group; X denotes CH or a nitrogen atom and Y denotes a halogen atom.
EFFECT: compounds have anti-tumour activity, balanced with toxicity level, and can be used as an active ingredient for producing a drug for treating malignant diseases.
11 cl, 4 dwg, 4 tbl, 24 ex
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