METHOD FOR ENHANCING TARGETED EDITING OF THE CXCR4 GENE IN HUMAN CD4 LYMPHOCYTES IN ORDER TO CREATE CELL RESISTANCE TO HIV-1 Russian patent published in 2022 - IPC C07K14/16 C12N15/07 C12N15/13 A61K48/00 A61P31/18 

Abstract RU 2779300 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biochemistry, in particular to donor DNA for the delivery of a protective peptide from gp41 MT-C34. Methods for delivery of a protective peptide from gp41 MT-C34 are also disclosed.

EFFECT: invention makes it possible to effectively edit the CXCR4 gene in CD4 lymphocytes.

3 cl, 4 dwg, 2 ex

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RU 2 779 300 C1

Authors

Maslennikova Aleksandra Konstantsiia

Kruglova Nataliia

Mazurov Dmitriy

Komkov Dmitrii Sergeevich

Dates

2022-09-05Published

2021-10-27Filed