FIELD: medicine.
SUBSTANCE: polymerase chain reaction is used in biological objects to determine allele G in locus rs 1042173 of gene SLC6A4 of the serotonin neurotransmitter system, and an allele specified in a group of genes of the dopamine neurotransmitter system: G in locus rs4680 of gene COMT, G in locus rs 17851478 and/or C in locus rs 1611115 of gene DBH, C in locus rs6275 of gene DRD2. If observing at least one risk allele in the both systems, a genetic predisposition to the development of psychoactive substance abuse is stated.
EFFECT: more accurate assessment of the risk of psychoactive substance abuse ensured by selecting the optimal system of neurotransmitter markers.
6 ex
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Authors
Dates
2014-01-27—Published
2012-06-06—Filed