MULTIPLEX SET OF MARKERS AS TOOL FOR DEVELOPING GENETIC TESTING OF SUSCEPTIBILITY TO SCHIZOPHRENIA, ALCOHOLISM AND CONNECTION WITH PERSONALITY TRAITS IN YOUNG PEOPLE AND MENTAL ABILITIES IN OLD AGE Russian patent published in 2024 - IPC C12Q1/68 C12Q1/6876 

FIELD: biotechnology.

SUBSTANCE: described is a set of synthetic oligonucleotide primers, which are nucleotide sequences SEQ ID NO: 1–81 and determining 27 single-nucleotide polymorphic variants capable of multiplexing, including rs11191580, rs11919880, rs12140439, rs12625893, rs12989701, rs1466662, rs1532278, rs1635, rs16887244, rs17594526, rs17693963, rs2075650, rs2279590, rs3772130, rs433598, rs454510, rs472926, rs530965, rs5860563, rs6265, rs6480463, rs6574433, rs671, rs7412, rs750338, rs7561528, rs9491140. Kit is intended for developing population-oriented genetic test systems for predicting the risk of schizophrenia, alcoholism, assessing cognitive abilities in old age and personality accentuations in young people.

EFFECT: kit will make it possible to form test systems, taking into account genetic characteristics of different populations, intended for genetic prediction of predisposition to schizophrenia, alcoholism, personality traits in young age and level of cognitive abilities in old age.

1 cl, 4 tbl