STRAIN OF DIPLOID CELLS OF LAMB SYNOVIAL MEMBRANE Ovis aries USED FOR VIROLOGICAL INVESTIGATIONS Russian patent published in 2014 - IPC C12N5/77 G01N33/569 

FIELD: biotechnologies.

SUBSTANCE: strain of diploid cells of lamb synovial membrane is obtained by culture method of growing tissular explants in DMEM nutritional medium with 10% of fetal bovine serum (FBS). Strain of lamb synovial membrane cells is sensitive to lentiviruses of small-size ruminants (goat arthritis-encephalitis virus and visna-maedi virus). Strain of lamb synovial membrane cells is stored in cell culture collection of All-Russian Research Institute of Veterinary Virology and Microbiology under number 64 and is deposited in Specialised collection of transferred somatic cell cultures of agricultural and field animals in All-Russian Research Institute of experimental veterinary named after Ya. R. Kovalenko under number 82.

EFFECT: obtaining strain of diploid cells of lamb synovial membrane Ovis aries, stable by biological characteristics, acceptable for scientific research and diagnostic work, characterised by permissiveness to lentiviruses of small-size ruminants, acceptable for scientific research and development of new antigenic preparations.

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