FIELD: biotechnologies.
SUBSTANCE: invention refers to markers system presenting a group of micro-RNA genes: miR-129-2, miR-125bl, miR-137 and miR-375 for diagnostics of non-small-cell lung cancer including epidermoid cancer and adenocarcinoma. Detection of methylation of at least one marker from this system serves as a diagnostic feature.
EFFECT: markers system allows detection of non-small-cell lung cancer at early clinical states of disease with high clinical sensitivity and specificity.
4 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| DIAGNOSTIC TECHNIQUE FOR NON-SMALL CELL CARCINOMA OF LUNG AND KIT FOR IMPLEMENTATION THEREOF | 2008 |
|
RU2390780C1 |
| DIAGNOSING TECHNIQUE FOR NON-SMALL-CELL LUNG CANCER AND SET FOR IMPLEMENTING THEREOF | 2010 |
|
RU2445627C1 |
| DETERMINING mRNA LEVEL REDUCTION IN GENES ITGA9, HYAL1 AND HYAL2 AS METHOD OF DIAGNOSING NON-SMALL CELL LUNG CANCER AND SET FOR ITS REALISATION | 2008 |
|
RU2403575C2 |
| METHOD OF MONITORING EFFICIENCY OF ANTICANCER THERAPY OF NON-SMALL CELL LUNG CANCER | 2015 |
|
RU2611340C2 |
| DIAGNOSTIC TECHNIQUE FOR CLEAR CELL RENAL ADENOCARCINOMA AND SET FOR IMPLEMENTATION THEREOF | 2009 |
|
RU2393472C1 |
| METHOD OF DIAGNOSING NON-SMALL CELL LUNG CANCER AND SET FOR REALISING IT | 2007 |
|
RU2351936C1 |
| METHOD OF EPIDERMOID LUNG CANCER DIAGNOSTICS AND RELATED SET | 2006 |
|
RU2327162C1 |
| METHOD OF DIAGNOSIS OF CLEAR CELL RENAL CELL CARCINOMA AND METHOD FOR PREDICTION OF METASTASIS BASED ON MIRNA GENES GROUP | 2017 |
|
RU2683251C1 |
| METHOD OF NON-SMALL CELL LUNG CARCINOMA DIAGNOSTICS AND RELATED ANALYSIS SET | 2006 |
|
RU2330285C1 |
| METHOD FOR DIAGNOSING OVARIAN CANCER BASED ON A GROUP OF microRNA GENES | 2018 |
|
RU2703399C1 |
