METHOD AND DEVICE FOR SIMULATING INFECTED ORAL MUCOSA WOUND IN EXPERIMENT Russian patent published in 2014 - IPC G09B23/28 

FIELD: medicine.

SUBSTANCE: infected oral mucosa wound is simulated on an internal surface of an animal's lower lip along the midline. That is ensured by applying original retractor clamps according to cl. 2 on the lower lip skin and mucosa. Branches of a Bilroth's hemostatic forceps are used to fix an oral mucosa area 2 mm² to be turned about a longitudinal axis at an angle of 360°. The mucosa is detached towards the operator. The prepared wound is covered with a cultured bacterial suspension in the amount of 2 ml. The method is implemented with using a device that is the original retractor clamps comprising two plates placed on the lower lip skin and mucosa, coupled with a spring hinge and merging into retractor clamps levers. The plate placed onto the lower lip mucosa has a sharp edged hole of the diameter of 5 mm. The plate placed onto the lower lip skin has a knop having the diameter of 3.5 mm and the height of 2 mm. The inventions may be also used in experimental medicine to study the efficacy of new pharmaceutical preparations on the oral mucosal wound process in experimental animals.

EFFECT: inventions enable simulating the natural oral mucosal wound process in the animals, make the studied area anatomically accessible, and normalise the wound surface.

2 cl, 2 ex, 1 dwg