METHOD FOR DETERMINING PROBABILITY OF THERAPEUTIC RESPONSE ON CANCER THERAPY WITH CARDIAC GLYCOSIDE Russian patent published in 2014 - IPC A61K31/704 A61K31/58 G01N33/53 G01N33/574 

Abstract RU 2508114 C2

FIELD: medicine.

SUBSTANCE: present invention refers to prognostic analysis, as well as to a method for applying it for determining a probability of producing a therapeutic response in the affected cells or tissues on treating a disease having an aethiology related to excessive cell proliferation with using cardiac glycoside. The method for prediction consists in determining the relation of Na, K-adenosine triphosphatase α-subunit isoforms in the affected cells or tissues. The above method can be used for the prediction of individual's cancer or tumour sensitivity to the therapeutic treatment with cardiac glycoside.

EFFECT: predicted method can be applied in a method of treating a disease or a disorder having an aethiology related to excess cell proliferation with using the composition containing cardiac glycoside.

59 cl, 9 tbl, 27 ex, 13 dwg

Similar patents RU2508114C2

Title Year Author Number
KIT FOR DETECTING PROBABILITY OF THERAPEUTIC RESPONSE TO ANTI-CANCER CHEMOTHERAPY WITH CARDIAC GLYCOSIDE 2008
  • N'Juman Robert A.
  • Jang Pejing
  • Ehddington O. Krehndell
RU2571687C2
METHOD OF TREATING NEUROLOGICAL DISORDERS WITH CARDIAC GLYCOSIDES 2011
  • Eddington Otis S.
  • Njuman Robert A.
RU2582223C2
METHOD OF TREATING NEUROLOGICAL CONDITIONS WITH CARDIAC GLYCOSIDS 2011
  • Eddington Otis S.
  • Nyuman Robert A.
RU2674679C2
METHOD FOR CELL PROTECTION AGAINST HYPOXIC INJURY BY GLUTATHIONYLATION OF Na, K-ADENOSINE TRIPHOSPHATASE CATALYTIC SUBUNIT 2013
  • Makarov Aleksandr Aleksandrovich
  • Petrushanko Irina Jur'Evna
  • Mit'Kevich Vladimir Aleksandrovich
  • Burnysheva Ksenija Mikhajlovna
  • Simonenko Ol'Ga Vasil'Evna
  • Lopina Ol'Ga Dmitrievna
  • Klimanova Elizaveta Andreevna
  • Dergousova Elena Aleksandrovna
RU2544958C2
METHOD OF IN VITRO DETERMINATION OF PROGNOSIS OF DISEASE DEVELOPMENT IN PATIENT WITH CANCER AND METHOD OF IN VITRO MONITORING EFFECT OF THERAPY ADMINISTERED TO PATIENT WITH CANCER 2006
  • Lakal' Sankhuan Khuan Karlos
  • Ramires De Molina Ana
  • Gallego Ortega David
  • Ban'Es Koronel' Monika
RU2434946C2
SUPERCRITICAL LIQUID EXTRACT CONTAINING CARDIAC GLYCOSIDE 2006
  • Ehddington Krehndell
  • Chzhan Fyn
  • Kouleng Dzhon Dzh.
RU2398591C2
HUMAN EZH2 INHIBITORS AND METHODS FOR APPLICATION THEREOF 2011
  • Copeland, Robert Allen
  • Richon, Victoria Marie
  • Scott, Margaret Davis
  • Sneeringer, Christopher John
  • Kuntz, Kevin Wayne
  • Knutson, Sarah Kathleen
  • Pollock, Roy Macfarlane
RU2765155C2
ANTIFIBROLYTIC MEANS 2016
  • Orlov Sergej Nikolaevich
RU2621299C1
ANTIFIBROLYTIC MEANS 2016
  • Orlov Sergej Nikolaevich
RU2621163C1
HUMAN EZH2 INHIBITORS AND METHODS OF APPLICATION THEREOF 2011
  • Kouplend Robert Allen
  • Richon Viktoriya Mari
  • Skott Margaret Devis
  • Sniringer Kristofer Dzhon
  • Kuntts Kevin Uejn
  • Natson Sara Kejtlin
  • Pollok Roj Makfarlejn
RU2618475C2

RU 2 508 114 C2

Authors

N'Juman Robert A.

Jang Pejing

Ehddington O. Krehndell

Dates

2014-02-27Published

2008-11-06Filed