FIELD: medicine.
SUBSTANCE: present invention refers to a kit applicable in a prognostic method in vitro for detecting or predicting in vivo therapeutic response in involved cells or tissues to treating a disease having an aetiology related to cell overproliferation, with the use of a cardiac glycoside. The described kit is used to detect a ratio of isoforms of Na,K-adenosine triphosphatase α-subunits in the involved cells or tissues. The above kit may be used to predict individual's cancer or tumour sensibility to the therapeutic treatment with a cardiac glycoside.
EFFECT: said kit may be used in a method of treating a disease or a disorder having an aetiology related to cell overproliferation, with the use of the composition containing a cardiac glycoside.
50 cl, 7 dwg, 8 tbl, 27 ex
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