FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to dermatology. To predict the deterioration probability of the clinical course of psoriasis, the progression into erythroderma, an integrated assessment of a pathoigenetic significance of the detected risk factors promoting the deterioration is made. What is determined is a prognostic coefficient (PC) for such criteria, as: sex; age; petrochemical workers; agricultural workers; construction workers; drivers; office staff; hyper insolation; adverse agricultural labour conditions (pesticide and fertiliser contact); petroleum contact; construction material contact; drug abuse; pockets of chronic bacterial and/or mycotic infections; frequent acute respiratory viral infections; chronic gastrointestinal and/or hepatic diseases; chronic pulmonary diseases; chronic respiratory infections; chronic otorhinolaryngological organs; disturbed liver detoxification; liver metabolic disturbance; circulating immune complex increase; immunoglobulin increase; immunoregulatory index decrease; stimulation index decrease; cytotoxic index decrease; antitissue autoantibody increase; blood skin antigen; leukocyte migration inhibition index increase. If a factor is absent, the related PC is considered to be zero. The derived PCs are summed up. If PC is 5.64-16.24, the low deterioration probability of the clinical course of psoriasis and the favourable prognosis; the PC value being 16.25-26.85 shows the medium deterioration probability and the relatively favourable prognosis; the value of 26.86-37.86 and more provides the high probability and the unfavourable prognosis, and the potential progression into erythroderma.
EFFECT: method enables predicting the deterioration probability of the clinical course of psoriasis, the progression into erythroderma.
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