METHOD FOR BIOCOMPATIBLE POLYMERIC STRUCTURE FORMATION Russian patent published in 2014 - IPC A61F2/28 A61N2/02 A61N2/06 A61K33/26 A61K31/74 A61K47/40 A61P19/00 A61M31/00 

Abstract RU 2512950 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to traumatology and biotechnology, and may be used for the biocompatible polymeric structure formation in bone tissues. That is provided by a puncture approach to a filled cavity in the bone tissues. That is followed by filling the cavity with a polymeric gel compound containing 55-97.7 wt % of the biocompatible polymer polylactide of a particle size of 50 to 100 mcm, 0.3-45 wt % of magnetic nanoparticles of ferric oxide of a particle size of 10 to 100 nm, the gelling agent maltodexrin in the amount of 0.5 to 50 wt % of the weight of mixed polymer and magnetic nanoparticles, as well as distilled water in the amount of 0.5 to 100 wt % of the weight of a dry mixture of the polymer, magnetic nanoparticles and gelling agent. A solid three-dimension structure is formed. That is accompanied with heating the compound throughout by exposing to an alternating magnetic field at frequency 500 kHz and amplitude 500 E for 3-5 minutes. Where appropriate slow down the process of heating the compound, it is additionally exposed to a direct magnetic field at amplitude 1000 E applied either to the whole formed volume, or locally depending on the problem to be solved.

EFFECT: method enables forming the biocompatible three-dimension structure in the specified cavity of the bone tissue with minimum surgical intervention.

1 dwg

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RU 2 512 950 C2

Authors

Gudoshnikov Sergej Aleksandrovich

Ljubimov Boris Jakovlevich

Popova Anastasija Vladimirovna

Usov Nikolaj Aleksandrovich

Dates

2014-04-10Published

2012-07-06Filed