FIELD: chemistry.
SUBSTANCE: described is pentamycin in form of polymorph A, which has chemical purity higher than 95%, which can be obtained in form of solvate with morpholine (molar ratio 1:1) or N-methylpyrrolidone (molar ratio 1:1), method of pentamycin purification by conversion of pentamycin with chemical purity lower than 93% into suitable solvate with morpholine or N-methylpyrrolidone, purification of solvate by crystallisation and release of pentamycin from solvate, as well as method of considerable reduction of rate of degradation of pentamycin with purity higher than 95%, by conversion into its polymorph A. Also described is application of pentamycin solvate with morpholine or N-methylpyrrolidone for chemical pentamycin purification.
EFFECT: obtaining of highly pure pentamycin.
11 cl, 14 dwg, 10 ex
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