PYRIMIDOPYRIDAZINE DERIVATIVES APPLICABLE AS P38 MAP KINASE Russian patent published in 2014 - IPC C07D237/18 C07D487/04 A61K31/50 A61K31/519 A61K31/5377 A61P11/00

Abstract RU 2516466 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to a compound of formula (IA) or (IB), or a pharmacologically acceptable salts thereof, wherein R^2a, R^2b, R^2c are independently specified in H, halogen and C₁-C₆alkyl; Y represents -O- or -S(O)_p-, wherein p is equal to 0, 1 or 2; and R¹ represents a radical of formula (IIC), wherein T represents -N or -CH; R³ represents H or F.

EFFECT: invention refers to a pharmaceutical composition possessing activity inhibiting p38 MAP kinase, and using them for treating bronchopulmonary diseases.

15 cl, 4 tbl, 2 ex

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RU 2 516 466 C2

Authors

Besvik Amanda

Vashkovych Bogdan

Dates

2014-05-20—Published

2010-02-16—Filed