METHOD OF INCREASING WATER SOLUBILITY OF LOW-SOLUBILITY SUBSTANCES Russian patent published in 2014 - IPC A61K47/02 A61K9/14 B01J13/00

Abstract RU 2517111 C2

FIELD: chemistry.

SUBSTANCE: present invention relates to a method of increasing water solubility of a low-solubility substance used in pharmaceutical products, veterinary pharmaceutical products, cosmeceuticals, cosmetic products, food products, agricultural chemicals etc. The method of increasing water solubility involves depositing a coating of microparticles of a low-solubility calcium compound, e.g. calcium phosphate or calcium carbonate, on the surface of particles of a low-solubility substance using mechanical energy to allow microparticles of the low-solubility calcium compound to penetrate particles of the low-solubility substance used in pharmaceutical products, veterinary pharmaceutical products, cosmeceuticals, cosmetic products, food products, agricultural chemicals etc.

EFFECT: high water solubility of the low-solubility substance.

14 cl, 99 tbl, 8 ex, 20 dwg

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RU 2 517 111 C2

Authors

Sakuma Shuji

Kikukawa Keiichiro

Miyasaka Ryosuke

Dates

2014-05-27—Published

2010-09-10—Filed