PRODUCING METHOD OF NANOCRYSTALLINE SILICON-REPLACED HYDROXYAPATITE Russian patent published in 2013 - IPC C30B29/14 C01B25/32 C01B33/24 A61L27/12 B82B3/00 B82Y30/00 

FIELD: metallurgy.

SUBSTANCE: producing method of monophasic nanocrystalline silicon-replaced hydroxyapatite involves synthesis of silicon-containing hydroxyapatite by means of a method for deposition from water solution of reagents containing orthophosphoric acid, calcium hydroxide and tetraethyl orthosilicate at pH of not less than 9 and molar ratio of Ca/P in the range of 2.0 to 2.5; sedimentation for completion of a phase formation process, extraction of deposit, drying and heat treatment of deposit; with that, synthesis is performed by adding 10-20% solution of orthophosphoric acid at the speed of 0.2-0.8 ml/min per litre of water solution of calcium hydroxide / tetraethyl orthosilicate composition prepared by means of 0.08-0.16% water solution of calcium hydroxide and design amount of tetraethyl orthosilicate to obtain a finished product with silicon replacement degree x equal to 1-2 and molar ratio of Ca/(P+Si), which is close to 1.67, and heat treatment is performed at the temperature of not lower than 300°C, but not higher than 400°C. Invention allows obtaining stoichiometric monophasic product of phases with average size of crystals of 9.95-12.53 nm, specific surface of 108.97-132.58 m²/g, and increased bioactivity, at the heating of which incidental phases do not occur.

EFFECT: improvement of characteristics.

4 dwg, 2 tbl, 8 ex