METHOD FOR PRODUCING BIOACTIVE HYDROXYAPATITE Russian patent published in 2016 - IPC A61L27/12 A61K35/32 C01B25/32 

Abstract RU 2604411 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine. Described is a method for producing bioactive hydroxyapatite, comprising cleaning bones by boiling in calcium chloride solution with concentration of 5-50 wt%. at the temperature of 105-130 °C for 1-2 hours, dissolving bovine bone tissue in hydrochloric acid with concentration of 2-8 wt%. and depositing hydroxyapatite with ammonium hydroxide solution with concentration of 20-25 wt%. while stirring to obtain the pH value of 8-9, pulping the residue after filtration in hot distilled water, repeated filtration and washing precipitate on filter with 2-3 portions of distilled water, then, with ethyl alcohol solution of 60-96 % concentration, drying at temperature of 100-120 °C, calcining at 700-900 °C.

EFFECT: result is simplified and shorter time for cleaning of bone tissue of muscles and ligaments and high quality of hydroxyapatite.

1 cl, 2 tbl, 2 ex

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Authors

Guzeev Vitalij Vasilevich

Bychkov Vladimir Semenovich

Guzeeva Tatjana Ivanovna

Zelichenko Elena Alekseevna

Gurova Oksana Aleksandrovna

Shovkopljas Jurij Aleksandrovich

Dates

2016-12-10Published

2015-07-14Filed