METHOD OF ESTIMATING CONDITION OF BLOOD COAGULATION SYSTEM IN PATIENTS IN CRITICAL CONDITION Russian patent published in 2014 - IPC G01N33/48 

FIELD: medicine.

SUBSTANCE: invention relates to medicine and is intended for diagnosing disorders of homeostasis system. The following indices are determined: R₁, MA₁, G₁, LY30₁, LY30₂, ΔR, ΔK, ΔAngle, ΔMA, ΔG and ΔLY30. If R₁ is within the norm range, and ΔR is more than 9 min, deficiency of humoral factors of blood coagulation is diagnosed, in case of normal of MA₁ and G₁ indices, together with increase of parameters ΔMA and ΔG by more than 26 mm and 6 kDyn/cm², deficiency of fibrinogen (factor I) is diagnosed, in case of more than 8% increase of index LY30₁ simultaneously with increase of index LY30₂ - activation of plasmin-dependent fibrinolysis, and in case of more than 8% increase of index LY30₁ with normal index LY30₂ - increased retraction of blood clot (hyperactivity of platelets).

EFFECT: method represents express-diagnostics, makes it possible to detect disorders in hemocoagulation system of patients and injured people in critical condition, identify the character of the said disorders and functional activity of hemocoagulation system links, which makes it possible to determine directions of pathogenically founded therapy.

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