COCRYSTALLINE FORM OF FENBUFEN Russian patent published in 2014 - IPC C07C59/84 C07D241/24 A61K31/192 A61K31/4965 A61P29/00 A61P31/04 A61P31/06 

Abstract RU 2521572 C1

FIELD: chemistry.

SUBSTANCE: claimed is a cocrystalline form of fenbufen with pyrazinamide, where molar ratio of fenbufen with pyrazinamide constitutes 1:1, which has an endothermal peak from 148 to 152°C by the data of measurements by means of differential scanning calorimetry and peaks at 2θ(°) 7.38, 10.43, 11.04, 21.67 by the data of measurement of polycrystal X-ray radiation diffraction.

EFFECT: increased rate and level of solubility of the crystalline form of fenbufen and its suitability for application in the pharmaceutical industry.

2 ex, 7 dwg

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RU 2 521 572 C1

Authors

Perlovich German Leonidovich

Manin Aleksej Nikolaevich

Manin Nikolaj Gennad'Evich

Voronin Aleksandr Pavlovich

Dates

2014-06-27Published

2012-12-21Filed