FIELD: medicine, pharmaceutics.
SUBSTANCE: described is a novel compound of formula I
,
where X and Y stand for O or S, R, R3, G1- G3 stand for H or C1-9alkyl; R1 and R2 is H or C1-4alkyl; R4 is H or phenyl; G4- G6 and G8- G9 are H; G7 is trifluoromethyl, a pharmaceutical composition containing it, methods of obtaining, an initial compound in methods described and a method of obtaining the initial compound and application of the formula I compound for treatment or prevention of a disease by activation of receptor δ(PPARδ); the said disease represents metabolic syndrome, obesity, dyslipidemia, pathological glycemia, insulin resistance, senile dementia and tumours.
EFFECT: obtaining the formula I compounds for treatment or prevention of the disease by activation of receptor δ(PPARδ).
20 cl, 47 ex, 3 dwg, 5 tbl
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