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2 175 319

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IPC

(21) (22)

Application

99104179/04, 1997-07-30

(24)

Start date

1997-07-30

(22)

Actual filing date

1997-07-30

(45)

Published

2001-10-27

(72)

Inventor

Romin Dzheffri L.Martin Skott V.Khevavasam PiasenaMinvell Nikolas A.Gribkoff Valentin K.Stehrrett Dzhon E. Dzhr.

(73)

Holder

Bristol-Maers Skvibb Kompani

DIPHENYL HETEROCYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD OF TREATMENT Russian patent published in 2001 - IPC

Abstract RU 2175319 C2

FIELD: organic chemistry, heterocyclic compounds, pharmacy. SUBSTANCE: invention relates to diphenyl heterocyclic compounds of the formula (I) where Het means fragment taken among the group consisting of (A) , (B) , (C) , (D) , (E) , (F) , (G) , (H) . These compounds are modulators of calcium-activated potassium channels of high conductivity and therefore they can be used for protection of nerve cells, especially in treatment and prophylaxis of patients with ischemia attack. Invention relates to also method of treatment of patients with new compounds and to pharmaceutical composition containing these compounds. EFFECT: improved method of treatment, valuable medicinal properties. 19 cl, 1 tbl, 146 ex

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RU 2 175 319 C2

Authors

Romin Dzheffri L.

Martin Skott V.

Khevavasam Piasena

Minvell Nikolas A.

Gribkoff Valentin K.

Stehrrett Dzhon E. Dzhr.

Dates

2001-10-27—Published

1997-07-30—Filed