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2 522 804

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IPC

C12P13/02(2006-01-01)

C12N9/80(2006-01-01)

C12N1/21(2006-01-01)

C12N15/52(2006-01-01)

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Application

2012143354/10, 2012-10-10

(24)

Start date

2012-10-10

(22)

Actual filing date

2012-10-10

(45)

Published

2014-07-20

(72)

Inventor

Lavrov Konstantin Valer'EvichLarikova Galina AndreevnaJanenko Aleksandr Stepanovich

(73)

Holder

Federal'Noe Gosudarstvennoe Unitarnoe Predprijatie Nauchno-Issledovatel'Skij Institut Genetiki I Selektsii Promyshlennykh Mikroorganizmov"

METHOD OF SYNTHESIS OF N-SUBSTITUTED ACRYLAMIDES AND RECOMBINANT STRAIN Rhodococcus erythropolis FOR ITS IMPLEMENTATION (VERSIONS) Russian patent published in 2014 - IPC C12P13/02 C12N9/80 C12N1/21 C12N15/52

Abstract RU 2522804 C2

FIELD: biotechnology.

SUBSTANCE: recombinant strains Rhodococcus erythropolis 37 p16-Ami RNCIM Ac-1937 and Rhodococcus erythropolis HX7 p16-Ami RNCIM Ac-1938 are constructed, constitutively producing the enzyme acylamidase with acylating activity. Also, the method of synthesis of N-substituted acrylamides is created, in particular N-isopropylacrylamide, and N-dimethylaminopropylacrylamide, using these strains as a biocatalyst.

EFFECT: invention enables to improve the efficiency of preparing N-substituted acrylamides.

3 cl, 1 tbl, 1 dwg, 9 ex

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RU 2 522 804 C2

Authors

Lavrov Konstantin Valer'Evich

Larikova Galina Andreevna

Janenko Aleksandr Stepanovich

Dates

2014-07-20—Published

2012-10-10—Filed