METHOD FOR ASSESSING RISK OF DEVELOPING CERVICAL CANCER FORMATION IN FEMALES WITH HUMAN PAPILLOMAVIRUS INFECTION Russian patent published in 2014 - IPC G01N33/53 

Abstract RU 2522908 C1

FIELD: medicine.

SUBSTANCE: cervical biopsy material tissues taken by colposcopic biopsy are examined for typing a human papillomavirus (HPV), apoptosis values (sFAS, TRAIL), genetic characteristics of expression of the genes regulating apoptosis processes, as well as radical formation processes (pyeloperoxidase activity, nitrate-nitrite levels, total antioxidant tissue capacity by the Fenton-type reaction). A summing risk factor of developing cervical cancer formation is calculated by formula. If the summing risk factor K is less than 3, then a low risk of cancer formation is predicted; if K is 3 or more, the risk of cancer formation is considered to be high.

EFFECT: applicability of the given method before the pathological processes are formed in tissues that let doctors prescribe a preventive course and prevent developing cervical cancer if having a predisposition observed or the risk factors detected, applicability of the given method with a diagnosed cervical pathology for the purpose of predicting the disease and monitoring of the efficacy of the conducted therapy.

2 ex

Similar patents RU2522908C1

Title Year Author Number
USING COMPLEX OF ANTIOXIDANT VITAMINS AND AMINO ACIDS AS ADDITION TO STANDARD THERAPEUTIC APPROACHES AND METHOD OF TREATING PAPILLOMAVIRUS-ASSOCIATED PRE-MALIGNANT UTERINE DISEASES AND PREVENTING CANCER FORMATION ACCOMPANYING PAPILLOMAVIRUS INFECTION 2013
  • Kharaeva Zaira Feliksovna
  • Korkina Ljudmila Georgievna
  • Attoeva Dzhamilja Ismailovna
  • De Ljuka K'Jarra
RU2537233C2
METHOD OF COMBINED THERAPY OF CERVICAL DYSPLASIA ASSOCIATED WITH HUMAN PAPILLOMA VIRUSES 2019
  • Kiselev Vsevolod Ivanovich
RU2701525C1
3,3'-DIINDOLYLMETHANE (METINDOL)-BASE VAGINAL SUPPOSITORY 2006
  • Kiselev Vsevolod Ivanovich
RU2318510C1
PHARMACEUTICAL COMPOSITION FOR TREATMENT OF DYSPLASTIC PROCESSES OF CERVIX 2008
  • Kiselev Vsevolod Ivanovich
RU2395281C2
DIAGNOSTIC TECHNIQUE FOR HYPERPROLIFERATIVE CONDITIONS AND METHOD FOR ASSESSING RISK OF CERVICAL CANCER ACCOMPANYING CERVICAL INTRAEPITHELIAL NEOPLASIA AND PAPILLOMA VIRUS CARRIER STATE BY DETERMINIG MRNA OF FUNCTIONAL HUMAN GENE COMPLEX 2012
  • Burmenskaja Ol'Ga Vladimirovna
  • Nepsha Oksana Sergeevna
  • Rogovskaja Svetlana Mikhajlovna
  • Sabdulaeva Ehllina Khakimovna
  • Sukhikh Gennadij Tikhonovich
  • Trofimov Dmitrij Jur'Evich
RU2532344C2
METHOD FOR CERVICAL CARCINOGENESIS DETECTION 2015
  • Makkallini Vinchentso
  • Di Benedetto Dzhuzeppe
RU2702334C2
METHOD FOR PREDICTING THE PROGRESS OF PAPILLOMAVIRUS INFECTION IN PATIENTS WITH CHRONIC RECURRENT INFLUENZA ASSOCIATED CERVICITIS 2017
  • Lemyakina Elena Viktorovna
RU2646785C1
METHOD OF COMPLEX THERAPY OF PRE-INVASIVE AND INVASIVE CERVICAL CANCER 2013
  • Kovchur Pavel Ivanovich
  • Bekker German Petrovich
  • Kim Su In
RU2560689C2
METHOD FOR RECURRENCE-FREE SURVIVAL AND OVERALL SURVIVAL IN HPV 16-POSITIVE CERVICAL CANCER PATIENTS 2018
  • Ibragimova Marina Konstantinovna
  • Tsyganov Matvej Mikhajlovich
  • Deryusheva Irina Valerevna
  • Churuksaeva Olga Nikolaevna
  • Shpileva Olga Vladimirovna
  • Kolomiets Larisa Aleksandrovna
  • Litvyakov Nikolaj Vasilevich
RU2694834C1
METHOD FOR ASSESSING CONDITIONS OF PROLIFERATIVE CERVICAL DISEASES 2012
  • Kiseleva Valentina Ivanovna
  • Zamulaeva Irina Aleksandrovna
  • Krikunova Ljudmila Ivanovna
  • Mkrtchjan Liana Sirekanovna
  • Kuevda Dmitrij Aleksandrovich
  • Saenko Aleksandr Semenovich
  • Tsyb Anatolij Fedorovich
  • Gorbushin Nikolaj Grigor'Evich
RU2503960C1

RU 2 522 908 C1

Authors

Kharaeva Zaira Feliksovna

Mikhal'Chik Elena Vladimirovna

Shevchenko Anna Aleksandrovna

Kuz'Mitskaja Esenija Fedorovna

Korkina Ljudmila Georgievna

Dates

2014-07-20Published

2012-12-24Filed