FIELD: medicine.
SUBSTANCE: cervical biopsy material tissues taken by colposcopic biopsy are examined for typing a human papillomavirus (HPV), apoptosis values (sFAS, TRAIL), genetic characteristics of expression of the genes regulating apoptosis processes, as well as radical formation processes (pyeloperoxidase activity, nitrate-nitrite levels, total antioxidant tissue capacity by the Fenton-type reaction). A summing risk factor of developing cervical cancer formation is calculated by formula. If the summing risk factor K is less than 3, then a low risk of cancer formation is predicted; if K is 3 or more, the risk of cancer formation is considered to be high.
EFFECT: applicability of the given method before the pathological processes are formed in tissues that let doctors prescribe a preventive course and prevent developing cervical cancer if having a predisposition observed or the risk factors detected, applicability of the given method with a diagnosed cervical pathology for the purpose of predicting the disease and monitoring of the efficacy of the conducted therapy.
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Authors
Dates
2014-07-20—Published
2012-12-24—Filed