FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to oncogynaecology, and can be used for complex therapy of pre-invasive and invasive cervical cancer. For this purpose immunocorrective inductor based ob peptide Alloferon-1 is introduced after surgical ablation of tumour. As medication based on peptide Alloferon-1 used are injections of preparation "Allokin-alpha" lyophilisate to prepare solution for subcutaneous introduction. Preparation is introduced in one course of six injections with one day interval between injections. Expression of CD3, CD4, CD8, CD4+CD25+, CD95+ and activity of caspases in peripheral blood lymphocytes serve as markers of efficiency and adequacy of complex treatment.
EFFECT: application of claimed method makes it possible to carry out immune-correcting therapy with preparation "Allokin-alpha" at postoperative stage of treatment, with provision of effectiveness and efficiency of complex therapy.
9 tbl, 8 dwg
| Title | Year | Author | Number |
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| METHOD OF TREATING PAPILLOMA VIRAL INFECTIONS IMPLEMENTED THROUGH INTERLEUKIN-18 INDUCTION | 2010 |
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| DIFFERENTIAL DIAGNOSTIC TECHNIQUE FOR CERVICAL DYSPLASIA AND CERVICAL CANCER | 2012 |
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| METHOD OF COMBINED THERAPY OF CERVICAL DYSPLASIA ASSOCIATED WITH HUMAN PAPILLOMA VIRUSES | 2019 |
|
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| METHOD OF CHOOSING TACTICS OF MANAGING PATIENTS WITH CERVICAL NEOPLASIA | 2011 |
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RU2472424C1 |
| METHOD FOR DIFFERENTIAL DIAGNOSIS OF CERVICAL INTRAEPITHELIAL NEOPLASIA OF GRADE III AND MICROINVASIVE CERVICAL CANCER ASSOCIATED WITH HUMAN PAPILLOMA VIRUS | 2019 |
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| METHOD FOR PREDICTION OF PROGRESSION OF LOW-GRADE CERVICAL SQUAMOUS INTRAEPITHELIAL LESION WITH UNDERLYING HUMAN PAPILLOMAVIRUS INFECTION | 2021 |
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RU2766719C1 |
| MUCOSAL VACCINE FOR IMMUNE THERAPY OF DISEASES CAUSED BY HUMAN PAPILLOMA VIRUSES, AND RELATED THERAPY (VERSIONS) | 2008 |
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