FIELD: medicine, pharmaceutics.
SUBSTANCE: claimed invention relates to the field of biotechnology and virology. Described is a chimeric pestivirus, where the said chimeric pestivirus includes the cattle diarrhea virus, which does not express its homologous Erns protein. The said chimeric pestivirus expresses a heterologous Erns protein, originating from the other pestivirus, or a natural, synthetic or genetic version of the said heterologous Erns protein. Also described are methods and sets for treatment or prevention of propagation of the infection, caused by the cattle diarrhea virus, as well as methods for a differentiation between the vaccinated animals and the animals, infected with the virus of a wild type.
EFFECT: invention can be used as immunogenic compositions and vaccines in animal breeding.
13 cl, 4 tbl, 5 ex
| Title | Year | Author | Number |
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| MUTANT VIRUS OF BULL DIARRHEA | 2006 |
|
RU2394594C2 |
| BVDV VACCINE | 2011 |
|
RU2578943C2 |
| NOVEL VIRULENCE DETERMINANT WITHIN E2 STRUCTURAL GLYCOPROTEIN OF CLASSICAL SWINE FEVER VIRUS | 2007 |
|
RU2451746C2 |
| MUTANT PESTIVIRUS WITH MUTATIONS IN Core GENE AND AREA NS3 AND VACCINE ON ITS BASIS | 2009 |
|
RU2483106C2 |
| BOVINE VIRAL DIARRHOEA VIRUS TYPE 1B VACCINE COMPOSITIONS AND METHODS FOR PRODUCTION AND USE THEREOF | 2011 |
|
RU2595873C2 |
| METHOD OF BACTERINATION AGAINST INFECTION OF SPERMARIES BVDV | 2005 |
|
RU2335298C2 |
| PESTIVIRUSES | 2015 |
|
RU2710041C2 |
| RECOMBINANT CLASSICAL SWINE FEVER VIRUS (CSFV), WHICH CONTAINS MODIFIED PROTEIN E2, AND CREATION METHODS OF ABOVE DESCRIBED RECOMBINANT CSFV | 2009 |
|
RU2501854C2 |
| NEW ADJUVANT COMPOSITIONS | 2009 |
|
RU2510280C2 |
| NUCLEOTIDE SEQUENCE OF CLASSIC SWINE FEVER VIRUS (CSFV) (VARIANTS), POLYPEPTIDE CSFV, PESTOVIRAL VACCINE AGAINST CSFV, DIAGNOSTIC SET AND METHOD | 1995 |
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RU2201451C2 |
