FIELD: medicine.
SUBSTANCE: what is described is a combined bone allograft representing a non-demineralised bone block prepared of a donor's spongy bone and containing human type I collagen in the form of a fine-cellular sponge prepared by lyophilisation of the bone block impregnated with a collagen solution, throughout the bone block. What is described is a method for preparing the combined bone allograft providing preparing the non-demineralised bone block of the donor's spongy bone, impregnating the bone block with the human type I collagen solution and conducting lyophilisation under the conditions providing the collagen solution transformation into the fine-cellular sponge throughout the bone block.
EFFECT: biocompatible combined bone allograft possesses the mechanical strength, osteoconductive effect, and stimulates osteogenesis.
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