METHOD FOR MEASURING AMINO ACID ABSORPTION RATE IN DIGESTIVE TRACT Russian patent published in 2014 - IPC A61B5/15 G01N33/49 G01N33/50 

FIELD: medicine.

SUBSTANCE: fasting blood test and blood test following taking amino acid mixture are conducted. First, fasting circulating blood volume, hematocrit and total calculated blood amino acid nitrogen content are determined in the morning. That is followed by oral administration of amino acid solution 100.0 ml transported according to one of absorption options with the known concentration of the solution and the amino acid nitrogen content therein The circulating blood volume, the hematocrit and the total calculated amino acid nitrogen content are determined again 30, 40, 50, 60, and 70 minutes after the administration of the amino acid sequence. The blood samples are measured for an amino acid absorption ratio by formula: $$K=\frac{N_n\times CB{V}_n\times \left(100-H{t}_n/100\right)-N_1\times CB{V}_1\times \left(100-H{t}_1/100\right)}{N},$$ wherein K is the amino acid absorption ratio, N is the nitrogen content in the amino acid mixture, N₁ is a blood amino acid nitrogen value before taking amino acids, N_n is a blood amino acid nitrogen value after taking amino acids, CBV₁ is a circulatory blood volume before taking amino acids, CBV_n is a circulatory blood volume after taking amino acids, Ht₁ is a hematocrit value before taking amino acids, Ht_n is a hematocrit value after taking amino acids, n is a time following the oral administration of amino acids. Taking into account the ratio K and the time following the oral administration of amino acids, a diagram reflecting the amino acid absorption rate in the digestive tract is plotted.

EFFECT: method enables measuring the total amino acid absorption rate in the digestive tract taking into account the transport system characteristics.

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