USING ALGINATE OLIGOMERS IN BIOFILM CONTROL Russian patent published in 2014 - IPC C07H7/33 A61K31/715 A61P31/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions refers to biotechnology. What is presented is an in vitro method for controlling a biofilm containing gram-negative bacteria, gram-positive bacteria or yeast, involving the contact of the above biofilm and an alginate oligomer. The alginate oligomer has an average molecular weight of less than 20000 Da and at least 80% of G residues, particularly α-L-guluronic acid. For the purpose of controlling the biofilm, including a biofilm infection, the above alginate oligomer can be also used as a part of a kit or a cleaning composition combined with other ingredients, as well as an abiotic surface coating.

EFFECT: above alginate oligomer can be used for preparing a therapeutic agent for using in treating or preventing the biofilm infection in an individual.

88 cl, 10 dwg, 7 tbl, 15 ex