FIELD: medicine, pharmaceutics.
SUBSTANCE: presented group of inventions refers to health work. There is presented a method for increasing the anti-acinetobacter antibiotic efficacy, a method for controlling in vitro an acinetobacter contamination of a region and using an alginate oligomer for increasing the anti-acinetobacter antibiotic efficacy, wherein the antibiotic is specified in macrolides, β-lactams, tetracyclines and quinolones, and wherein the alginate oligomer has a degree of polimerisation from 2 to 100 and at least 70% of hyaluronic acid or guluronate residues or at least 70% of mannuronic acid or mannuronate residues. What is presented is a product containing the alginate oligomer and antibiotic in the form of a combination drug for separate, simultaneous or sequential use for increasing the efficacy of the above anti-acinetobacter antibiotic.
EFFECT: achieving the higher antibiotic efficacy against acinetobacters having multiple drug resistance.
14 cl, 5 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| ALGINATE OLIGOMERS APPLICABLE IN OVERCOMING MULTIPLE DRUG RESISTANCE IN BACTERIA | 2010 |
|
RU2582938C2 |
| USING ALGINATE OLIGOMERS IN BIOFILM CONTROL | 2008 |
|
RU2527894C2 |
| BACITRACIN-ALGINATE OLIGOMER CONJUGATES | 2017 |
|
RU2766345C2 |
| INHALABLE POWDERED COMPOSITIONS OF ALGINATE OLIGOMERS | 2015 |
|
RU2708397C1 |
| USE OF ALGINATE OLIGOMERS AS BLOOD ANTICOAGULANTS | 2014 |
|
RU2709814C1 |
| CONTROLLED-RELEASE DRUG SOLID PHARMACEUTICAL COMPOSITION | 1996 |
|
RU2142793C1 |
| USE OF LOW-DIMENSIONAL BIDIMENTIONAL (2D) FOLDED STRUCTURES OF ALUMINUM OXYHYDROXIDE (ALOOH) TO OVERCOME RESISTANCE OF BACTERIA TO ANTIBIOTICS | 2018 |
|
RU2705989C1 |
| COMPOSITION COMPRISING AN ANTIBIOTIC AND A DISPERSING AGENT OR AN ANTI-ADHESIVE AGENT | 2011 |
|
RU2739249C2 |
| COMPOSITION COMPRISING AN ANTIBIOTIC AND A DISPERSANT OR AN ANTI-ADHESIVE AGENT | 2011 |
|
RU2607660C2 |
| USING LEVOFLOXACIN IN AEROSOL FORM FOR TREATING MUCOVISCIDOSIS | 2010 |
|
RU2563809C2 |
