FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, in particular, to a conjugate of bacitracin and an alginate oligomer, and can be used in medicine. The invention allows for production of a bacitracin-alginate oligomer conjugate containing a bacitracin-class antibiotic covalently attached to at least one alginate oligomer by a direct covalent bond or a covalent molecular linker.
EFFECT: conjugate may be applicable in treatment or prevention of a bacterial infection in a subject with a bacterial infection, suspicion or risk of development thereof.
25 cl, 9 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| ALGINATE OLIGOMERS APPLICABLE IN OVERCOMING MULTIPLE DRUG RESISTANCE IN BACTERIA | 2010 |
|
RU2582938C2 |
| PROCESSING ACINETOBACTERS WITH ALGINATE OLIGOMERS AND ANTIBIOTICS | 2010 |
|
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| USING ALGINATE OLIGOMERS IN BIOFILM CONTROL | 2008 |
|
RU2527894C2 |
| USE OF ALGINATE OLIGOMERS AS BLOOD ANTICOAGULANTS | 2014 |
|
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| INHALABLE POWDERED COMPOSITIONS OF ALGINATE OLIGOMERS | 2015 |
|
RU2708397C1 |
| ANTIBODIES AGAINST TEICHOIC ACID CONJUGATE AND THEIR CONJUGATES | 2014 |
|
RU2687044C2 |
| METHODS AND REAGENTS FOR PREVENTING AND/OR TREATING AN INFECTION | 2015 |
|
RU2698099C2 |
| METHODS AND COMPOSITIONS DESCRIBED AS SYNTHETIC BETA-1,6-GLUCOSAMINOLIGOSACCHARIDES | 2009 |
|
RU2532911C2 |
| METHODS OF GLYCOGONJUGATION AND COMPOSITION | 2013 |
|
RU2645071C2 |
| IMMUNOSTIMULATING G,U-CONTAINING OLYGORIBONUCLEOTIDES | 2003 |
|
RU2302865C2 |
