METHOD AND DEVICE FOR QUANTIFICATION OF TARGET COMPONENTS WITH MAGNETIC LABELS Russian patent published in 2014 - IPC G01N33/543 

FIELD: measuring instrumentation.

SUBSTANCE: group of inventions refers to quantification of a target component in a sample, where magnetic particles can have specific links with contact surface. Method of target component quantification in a sample with specific links of magnetic particles (2) to contact surface (4) of chamber (1) filled with the sample with kinetics depending on the amount of target component in the samples involves the following stages: a) at least two flushing stages when magnetic force affects magnetic particles (2) so that unlinked magnetic particles move away from contact surface (4); b) at least two measurement stages, each related to one of flushing stages, when total amount of magnetic particles (2) on contact surface (4) is measured during flushing stage a), while duration and/or number of further flushing stages are determined on the basis of measurement results from previous flushing and measurement stages; c) assessment stage when amount of the target component (2) in the sample is assessed by at least one measurement result from stage b). In addition, invention describes device of the same purpose, data carrier with PC software for implementation of this method, and application of this sensor device for molecular diagnostics and for biological or chemical sampling.

EFFECT: improved reliability of quantification.

14 cl, 9 dwg