SELF-MICROEMULSIFIED ORAL PHARMACEUTICAL COMPOSITION CONTAINING HYDROPHILIC THERAPEUTIC AGENT, AND METHOD FOR PREPARING IT Russian patent published in 2014 - IPC A61K9/107 A61K31/4184 A61K31/7068 A61K47/00

Abstract RU 2532362 C2

FIELD: medicine.

SUBSTANCE: hydrophilic therapeutic agent is specified in a group consisting of albuterol, bendamustine, captopril, carboplatin, ciprofloxacin, gemcitabine, ibandronate, lamivudine, metformin, niacin, oxycodone, ranitidine and sumatriptan. The composition also contains a solvent, a surfactant and a hydrophilic carrier. The above hydrophilic carrier is compatible to the therapeutic agent solution and the surfactant.

EFFECT: good stability and bioavailability compatible to that of injection formulations when administered orally.

21 cl, 2 dwg, 13 tbl, 4 ex

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RU 2 532 362 C2

Authors

Khsu Chan-Shan'

Khao Vehj-Khua

Van Tszon-Tszin

Lin' Tsun-Khsyn

Dates

2014-11-10—Published

2010-04-27—Filed