PROFILES OF EXPRESSION OF GENES ASSOCIATED WITH LEAN PHENOTYPE Russian patent published in 2014 - IPC C12Q1/68 

FIELD: biotechnology.

SUBSTANCE: invention is a combination of polynucleotides or proteins expressed from them, which are differentially expressed in animals exhibiting lean phenotype which is a result of one or several lean phenotype stimulating treatments comprising administering CLA, the consumption of a diet with high protein content and increase in physical exercises. At that the polynucleotides are selected from genes encoding proteins differentially expressed in liver and muscle tissues, which ID are listed in Table 6F, or from genes encoding proteins differentially expressed in adipose tissue, liver tissue and muscle tissue, which ID are listed in Table 6G, or from their fragments.

EFFECT: invention discloses gene expression profiles associated with improved or maintained lean body mass and with reduced content of body fat.

13 cl, 13 tbl, 3 ex