FIELD: medicine; oncology.
SUBSTANCE: invention relates to medicine, namely to oncology, and can be used to treat a patient with a malignant neoplasm. The method involves administering to the patient therapeutically effective amounts of (16E) -14-methyl-20-oxa-5,7,14,26-tetraazatetracyclo [19.3.1.1 (2.6) .1 (8.12)] heptacose-1 (25 ), 2 (26), 3,5,8 (27), 9,11,16,21,23-decaene (TG02) or a pharmaceutically acceptable salt thereof in combination with radiation therapy, where the total dose of radiation received by the patient is ranges from 0.01 Gy to 100 Gy.
EFFECT: use of the invention makes it possible to increase antiproliferative activity due to the synergistic action of the combination.
10 cl, 4 tbl, 33 dwg, 11 ex
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