METHOD FOR ANTIBACTERIAL THERAPY IN GASTRIC CANCER PERFORATION Russian patent published in 2014 - IPC A61B17/00 A61K33/14 A61K31/4164 A61K33/00 A61P41/00 

FIELD: medicine.

SUBSTANCE: upon completion of the surgical intervention, before the abdominal wall closure, microirrigators are inserted through counteropenings into the hypochondria. An end of the right microirrigator is fixed with an interrupted catgut suture to a stump of the resected stomach; an end of the left microirrigator is fixed at an upper level of the abdominal cavity with the interrupted catgut suture. Drain tubes are inserted through the counteropenings in the iliac regions into the small pelvis. The surgical intervention is terminated with treating the whole abdominal cavity with 50 ml ozonised normal saline 1000 mcg/l. Then 10 minutes later, the abdominal cavity is treated with metronidazole 100 ml. From the 1^st to 5^th postoperative day, metronidazole 200 ml is administered in the form of 24-hour infusion through a portable infusion device via the right microirrigator. Through the left microirrigator, 50 ml ozonised normal saline 1000 mcg/l is administered once a day. A course of standard intravenous antibiotic therapy is prescribed into the patient.

EFFECT: reducing an incidence rate of postoperative infectious-inflammatory complications in the given category of patients due to the specific regimen of the antibacterial therapy and the ozone therapy.

2 ex