FIELD: chemistry.
SUBSTANCE: invention relates to chemistry of biologically active polymers. Described is a copolymer of N-vinylpyrrolidone and unsubstituted or substituted vinylpyridine, in which pyridine fragments are partially quaternized with methyl iodide, represented by general formula (I):
where R denotes hydrogen or methyl, content of n monomer links of N is 5–85 mol.%, content of q monomer links Q is 5–85 mol.%, content v of monomer links V is 10–75 mol.% provided that 25 mol.% ≤ q+n ≤ 90 mol.% and v+n+q=100 mol.%, and the viscosity-average molecular weight of the copolymer Mμ is equal to 16–302 kDa.
EFFECT: imparting antiviral properties to influenza A virus to copolymers based on N-vinylpyrrolidone and optionally methylated vinylpyridines, high solubility of the disclosed copolymers in aqueous weakly acidic and neutral media.
2 cl, 13 tbl, 10 ex
| Title | Year | Author | Number |
|---|---|---|---|
| COPOLYMER HAVING ACTIVITY AGAINST INFLUENZA TYPE A (VERSIONS), CONTAINING UNITS OF N-VINYLPYRROLIDONE AND OPTIONALLY C-METHYLATED VINYLPYRIDINE, COMPLETELY METHYL QUATERNIZED WITH METHYL IODIDE | 2023 |
|
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| N-VINYLPYRROLIDONE BASED COPOLYMERS | 2010 |
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| ANTIVIRAL AND IMMUNOMODULATING COMBINATION OF AMINOCAPROIC ACID AND COPOLYMER OF 2-METHYL-5-VINYLPYRIDINE AND N-VINYLPYRROLIDONE | 2017 |
|
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| COPOLYMERS OF 4-VINYLPYRIDINE OR 2-METHYL-5-VINYLPYRIDINE AND N-VINYLPYRROLIDONE WITH TERMINAL CYANOVALERIC ACID RESIDUE AND USE THEREOF TO TREAT PNEUMOCONIOSIS | 2014 |
|
RU2550820C1 |
| COPOLYMERS OF 2-METHYL-5-VINYL-PYRIDINE AND N-VINYL PYRROLIDONE, HAVING PHAGOCYTOSIS ACTIVATOR PROPERTIES | 2010 |
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| COPOLYMERS OF 2-METHYL-5-VINYL-PYRIDINE AND N-VINYLPYRROLIDONE, ACTIVATING PRODUCTION OF INTERLEUKIN-1, AND USE THEREOF AS ANTI-CANCER AGENTS | 2010 |
|
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| INTERPOLYMER POLYELECTROLYTE COMPLEX AND A PROLONGED IMMUNOSTIMULATING AGENT ON ITS BASIS, FOR MEDICAL AND VETERINARY USE | 2017 |
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RU2683947C1 |
