COPOLYMER CONTAINING N-VINYL PYRROLIDONE, 2-METHYL-5-VINYL PYRIDINE AND 4-VINYL PYRIDINE LINKS Russian patent published in 2012 - IPC C08F226/10 A61K31/79 

Abstract RU 2459838 C1

FIELD: chemistry.

SUBSTANCE: disclosed is a N-vinyl pyrrolidone-based copolymer of general formula (I): , where the monomer link M1 represents a fragment of 2-methyl-5-vinyl pyridine (MVP), and the monomer link M2 represents a fragment of 4-vinyl pyridine (VP): M1, (MVP) M2, (VP); content of monomer links M1 and M2 (m+k) is equal to 20-90 mol %, wherein the content of monomer links M2 (k) is equal to 0.05-(m+k)-0.30·(m+k), and the viscosity-average molecular weight Mµ of the copolymer Mµ=15-250 kDa. Also disclosed is use of said copolymer as an activator for producing interleukin-1, an agent against liver, kidney, urinary bladder, bone marrow and breast cancer, as a phagocytosis activator and as an adjuvant when influenza vaccines.

EFFECT: disclosed copolymer widens the range of biologically active compounds based on copolymers of N-vinyl pyrrolidone and has a wide range of action compared to existing analogues.

9 cl, 6 tbl, 14 ex

Similar patents RU2459838C1

Title Year Author Number
COPOLYMERS OF 2-METHYL-5-VINYL-PYRIDINE AND N-VINYL PYRROLIDONE, HAVING PHAGOCYTOSIS ACTIVATOR PROPERTIES 2010
  • Kedik Stanislav Anatol'Evich
  • Panov Aleksej Valer'Evich
  • Zajtsev Maksim Andreevich
  • Cherta Julija Vjacheslavovna
RU2430933C1
COPOLYMERS OF 4-VINYLPYRIDINE OR 2-METHYL-5-VINYLPYRIDINE AND N-VINYLPYRROLIDONE WITH TERMINAL CYANOVALERIC ACID RESIDUE AND USE THEREOF TO TREAT PNEUMOCONIOSIS 2014
  • Kedik Stanislav Anatol'Evich
  • Panov Aleksej Valer'Evich
  • Suslov Vasilij Viktorovich
  • Kochkina Julija Vjacheslavovna
  • Vorfolomeeva Elena Viktorovna
RU2550820C1
COPOLYMERS OF 2-METHYL-5-VINYL-PYRIDINE AND N-VINYLPYRROLIDONE, ACTIVATING PRODUCTION OF INTERLEUKIN-1, AND USE THEREOF AS ANTI-CANCER AGENTS 2010
  • Kedik Stanislav Anatol'Evich
  • Panov Aleksej Valer'Evich
  • Zajtsev Maksim Andreevich
  • Cherta Julija Vjacheslavovna
RU2430932C1
N-VINYLPYRROLIDONE-BASED COPOLYMERS IN FORM OF PHARMACEUTICALLY ACCEPTABLE SALTS OF ACIDS 2013
  • Kedik Stanislav Anatol'Evich
  • Panov Aleksej Valer'Evich
  • Suslov Vasilij Viktorovich
  • Eremin Dmitrij Viktorovich
  • Kochkina Julija Vjacheslavovna
RU2533113C1
N-VINYLPYRROLIDONE BASED COPOLYMERS 2010
  • Kedik Stanislav Anatol'Evich
  • Svergun Vjacheslav Ivanovich
  • Cherta Julija Vjacheslavovna
  • Jartsev Evgenij Ivanovich
  • Panov Aleksej Valer'Evich
RU2415876C1
USE OF N-VINYLPYRROLIDONE COPOLYMER AS AGENT POTENTIATING ANALGESIC EFFECT OF MORPHINE HYDROCHLORIDE 2011
  • Kedik Stanislav Anatol'Evich
  • Panov Aleksej Valer'Evich
  • Eremin Dmitrij Viktorovich
  • Suslov Vasilij Viktorovich
  • Kochkina Julija Vjacheslavovna
  • Sakaeva Irina Vjacheslavovna
RU2471491C1
OPHTHALMIC PREPARATION PRESENTED IN FORM OF EYE DROPS AND CONTAINING BRANCHED POLYHEXAMETHYLENE GUANIDINES AND POLY(N-VINYLPYRROLIDONE) 2012
  • Kedik Stanislav Anatol'Evich
  • Panov Aleksej Valer'Evich
  • Suslov Vasilij Viktorovich
  • Jartsev Evgenij Ivanovich
  • Kochkina Julija Vjacheslavovna
RU2509562C1
MEDICINAL AGENT BASED ON SYNTHETIC COPOLYMER OF VINYLPYRIDINE ROW FOR TREATING TISSUE HELMINTHIASIS 2019
  • Kedik Stanislav Anatolevich
  • Suslov Vasilij Viktorovich
  • Panov Aleksej Valerevich
  • Kochkina Yuliya Vyacheslavovna
  • Bogunova Irina Vladimirovna
  • Shatalov Denis Olegovich
  • Ajdakova Anna Viktorovna
  • Ivanov Ivan Sergeevich
  • Belyakov Sergej Vyacheslavovich
RU2727935C1
INTERPOLYMER POLYELECTROLYTE COMPLEX AND A PROLONGED IMMUNOSTIMULATING AGENT ON ITS BASIS, FOR MEDICAL AND VETERINARY USE 2017
  • Kedik Stanislav Anatolevich
  • Suslov Vasilij Viktorovich
  • Shnyak Elizaveta Aleksandrovna
  • Malkova Anastasiya Pavlovna
  • Domnina Yuliya Mikhajlovna
  • Kochkina Yuliya Vyacheslavovna
RU2683947C1
OPHTHALMIC PREPARATION PRESENTED IN FORM OF EYE DROPS AND CONTAINING BRANCHED POLYHEXAMETHYLENE GUANIDINES 2012
  • Kedik Stanislav Anatol'Evich
  • Panov Aleksej Valer'Evich
  • Suslov Vasilij Viktorovich
  • Jartsev Evgenij Ivanovich
  • Kochkina Julija Vjacheslavovna
RU2510264C1

RU 2 459 838 C1

Authors

Kedik Stanislav Anatol'Evich

Panov Aleksej Valer'Evich

Kochkina Julija Vjacheslavovna

Eremin Dmitrij Viktorovich

Sakaeva Irina Vjacheslavovna

Dates

2012-08-27Published

2011-10-05Filed